The purpose of this paper is to compare the prevalence of abnormal cholesterol in children, adolescent and adults in the United States. Data from the National Health and Nutrition Examination survey (NHANES) for 2011-2014 were obtained for the comparison. A t test statistical analysis was conducted at a significant level of p<0.05 to check for differences in the groups. The results of high total cholesterol and low high density lipoprotein (HDL) were compared in children, adolescent and adults according to race, sex and ethnicity. A total of 27.9% of men had low level of HDL cholesterol, 10% of women had low HDL,13.4% of children and adolescent had low level of HDL. Boys had low HDL (14.8%) while girls had 12%. The non-Hispanic black adults with elevated total high cholesterol was 8.6%, non-Hispanic white (12.5%), Hispanic adults (13.1%) while non-Hispanic black children and adolescent had elevated total high cholesterol, the non-Hispanic white and Hispanic adolescent and children had low total high cholesterol. The level of low HDL cholesterol was higher in children, adolescent and adult male population, the high total cholesterol was higher in the female children, adolescent and adults.